Diabetes mellitus, commonly known as diabetes, is a chronic metabolic disorder characterized by elevated blood glucose levels. This occurs either because the pancreas doesn't produce enough insulin or the body cannot effectively use the insulin it produces. Insulin, a hormone, is crucial for regulating blood glucose by allowing sugar to enter cells for energy. Uncontrolled diabetes leads to hyperglycemia, which, over time, can severely damage various bodily systems, especially nerves and blood vessels. There are primarily three types of diabetes: type 1, type 2, and gestational diabetes. Type 1 is an autoimmune condition where the body attacks insulin-producing cells. Type 2, the most common, involves insulin resistance. Gestational diabetes develops during pregnancy.
Globally, diabetes is a growing concern. The number of people living with diabetes rose from 200 million in 1990 to 830 million in 2022. In 2021, diabetes was the direct cause of 1.6 million deaths. In the United States, over 40 million people have diabetes, and it remains a leading cause of kidney failure, lower-limb amputations, and adult blindness. Alarmingly, over half of adults aged 30 years and over living with diabetes were not taking medication for their diabetes in 2022. While there is no cure for diabetes, management through a healthy diet, regular physical activity, weight management, and medication can significantly improve outcomes and prevent complications.