Chlorogenic acids (CGAs) are a family of phenolic compounds, specifically hydroxycinnamates, widely found in plants such as coffee beans, fruits (apples, pears, blueberries), and vegetables (artichokes, eggplant). CGA is an ester of caffeic acid and quinic acid and acts as a potent antioxidant. CGA plays roles in regulating glucose and lipid metabolism, and it may help improve insulin resistance. Research indicates potential health benefits, including antioxidant, anti-inflammatory, antibacterial, antiviral, anti-diabetic, and anticancer properties, as well as reducing the risk of cardiovascular diseases, type 2 diabetes, and Alzheimer's disease. CGA also contributes to the color and bitter taste of coffee.
The primary dietary sources of chlorogenic acids are coffee, green coffee beans, tea, sunflower seeds, apples, and blueberries. Green coffee beans contain a significant amount of chlorogenic acid, ranging from 5 to 12 percent of their total weight. The amount of CGA in coffee varies based on the coffee variety, roasting level, and brewing method. Light roast coffee generally contains the highest concentration. CGA is available for purchase from chemical suppliers like AdooQ and Thermo Fisher Scientific, typically for research purposes. The price for chlorogenic acid (98% HPLC) is approximately ฿89.95 per gram. Depending on the supplier and quantity, the price ranges from $30.00 for 500mg to $357.00 for 5g. Green coffee bean extracts with chlorogenic acids are also available from retailers like Walmart, with prices around $14.99.
