Amazon

The Collapse of Human Biosis For more than seventy years, humanity has engaged in a vast, silent chemical experiment. With the introduction of industrial antibiotics, pesticides, and herbicides, we have systematically targeted the microbial world. We operate under the delusion that our bodies are isolated, mechanical systems capable of withstanding this chemical barrage. This assumption is wrong. The human body is not an isolated machine; it is a complex, hyper-connected ecosystem. When we disrupt the relationships that make life possible—a concept known as **biosis**—the entire system begins to fail. In a profound exploration of human biology, ecology, and the history of industrial medicine, Dr. Zach Bush joined Joe Rogan to unpack why our current chemical-antibiotic era is failing and how a biological renaissance is emerging. Bush, a physician specializing in internal medicine, endocrinology, and hospice care, argues that our current global health crisis is not a random collection of chronic illnesses. Instead, it is the direct consequence of our radical separation from nature, accelerated by the commercialization of patented chemical compounds that disrupt human metabolism at its core. To understand how we arrived at this crisis, we must look past the symptoms of chronic disease and focus on the fundamental unit of biological energy: the mitochondria. Our bodies survive by concentrating light energy, converting the carbon bonds of carbohydrates and fats back into electromagnetic energy. By treating the Earth and our bodies with billions of pounds of chemical toxins, we have effectively choked off this energy production, sparking a cascade of metabolic and neurological collapse. The Commercialization of Abstract Molecules The pivot toward a chemical-dominated lifestyle did not happen by accident. It began in the early twentieth century when massive industrial interests realized they could maximize profits by manipulating natural compounds. In 1910, the Rockefeller Foundation funded the Flexner Report, an initiative that systematically discredited traditional herbal medicine and framed chemical, fossil-fuel-derived compounds as the only legitimate pathway to modern medical care. This shift introduced a profound abstraction into the human experience. In chemistry, a racemic mixture refers to a process where scientists create the mirror image of a natural molecule. Nature produces specific geometries of molecules that our bodies recognize and digest seamlessly. However, corporations cannot patent molecules that exist in nature. To commercialize biology, industries utilize chemical processes to flip these molecules. High Fructose Corn Syrup serves as a classic example of this mirror-image manipulation. While natural fructose is easily processed, its flipped chemical twin cannot be processed by the liver as a normal carbohydrate. Instead, the liver is forced to process this flipped molecule as an inflammatory triglyceride, leading to cardiovascular disease, brain inflammation, and severe metabolic disorders. This pattern of isolating plant compounds, flipping their chemical structures, patenting them, and selling them back to a compromised public became the foundational business model of the pharmaceutical and agricultural industries. During his academic career developing chemotherapies, Dr. Bush noticed a similar trend. Rather than nourishing and restoring communication to damaged, isolated cells, modern medicine focused almost entirely on poisoning them. This paradigm of "anti-everything"—antibiotics, anti-cancer, anti-obesity, and anti-diabetics—has built a multi-trillion-dollar chronic disease management system that relies on keeping humans sick to remain profitable. The Chilling Timeline of Glyphosate Poisoning At the center of our environmental and metabolic collapse is a single organophosphate molecule: glyphosate. Originally patented in the late 1950s by a Japanese inventor and used as an industrial pipe cleaner by Monsanto, glyphosate was repatented as an agricultural weed killer in 1976 under the name Roundup. Today, chemical farming systems spray billions of pounds of this antibiotic into global soils annually. Glyphosate is an exceptionally powerful chelator and antibiotic. When humans consume food carrying residues of this chemical, it devastates our cellular machinery. Specifically, it targets the mitochondria—the tiny, ancient bacteria living inside human cells that are responsible for producing adenosine triphosphate (**ATP**), our cellular energy. When exposed to even minuscule levels of glyphosate, mitochondrial ATP production collapses rapidly. Dr. Bush outlines a chilling, chronological timeline of how this energy collapse has manifested as a global epidemic of chronic diseases since the introduction of glyphosate: * **The 1980s (Obesity):** Four years after glyphosate entered our food system, global obesity rates began to climb. Obesity is not simply a result of overeating; it is a metabolic symptom of mitochondria that have been poisoned and can no longer burn calories. The body has no choice but to store this unburned fuel in the liver and fat tissues. * **The Early 1990s (Diabetes and Allergies):** As liver fat accumulated, insulin resistance developed, leading to a global surge in Type II Diabetes. Simultaneously, the immune system—the most energy-demanding system in the human body—began to fail due to metabolic starvation. Humans began reacting defensively to their environment, resulting in a sudden spike in asthma, food allergies, and gluten sensitivities. We do not have a gluten crisis; we have a metabolic collapse caused by glyphosate poisoning. * **The Late 1990s (Autoimmune Disease and Neurological Decay):** As our internal ecosystems degraded, our bodies lost their sense of cellular identity. The immune system, unable to distinguish between self and non-self, began attacking its own organs, triggering an explosion of autoimmune diseases. Shortly after, neurological degenerative disorders like Alzheimer's, Parkinson's, ADHD, and autism went logarithmic. * **The 2000s (The Cancer Epidemic):** Widespread cancer epidemics emerged, initially as leukemias and lymphomas, and later as aggressive solid tumors in the breast, prostate, and colon. This surge occurred not because of a sudden increase in carcinogens, but because the human body lacked the metabolic energy needed to maintain cellular communication and repair itself. * **The 2010s to Present (Fertility Collapse and Cellular Neutrality):** Today, more than 110 countries have fertility rates well below the threshold needed to replace their populations. Furthermore, this lack of cellular energy is disrupting biological development in the womb. Every fetus begins as biologically neutral. Moving from neutral to male or female requires a massive, coordinated discharge of mitochondrial energy at ninety days of gestation. Without this energy, the natural process of gender differentiation in the womb is disrupted, leading to widespread endocrine and developmental anomalies. Humans as a Biological Antenna To move past this era of chemical degradation, we must re-evaluate what we are. The traditional view of the human genome is incomplete. When scientists set out to map the human genome in the 1990s, they expected to find around 400,000 genes to match the number of proteins in our bodies. Instead, they discovered that humans possess fewer than 20,000 genes. This is less than a common flea, which has 30,000 genes. More astonishingly, only 1.5% of our DNA actually codes for human genes. The remaining 98.5% was dismissed by geneticists for decades as "junk DNA." We now know this DNA is not junk; it is an incredibly complex library of genetic information that we share with the microbial world. Mitochondria access our nucleus to retrieve genetic sequences for their own reproduction. This genetic reality suggests that the human body is not a single, isolated species. We are a walking, breathing ecosystem. Our DNA operates as a biological antenna system designed to receive, process, and transmit information from the cosmos and the Earth. When we are fully connected to natural systems, our antenna works at a massive bandwidth, allowing us to communicate with our environment, regulate our health, and maintain an incredibly high rate of cellular repair. When we separate ourselves from nature—by living in concrete boxes, eating sterile, chemically treated food, and relying on abstract monetary and pharmaceutical systems—our antenna signal degrades. The modern human exists in a state of sensory deficit, isolated and vulnerable to physical and psychological decay. This signal loss is what fuels modern addiction. Addiction is the predictable behavior of an organism that feels abandoned by its infinite, natural reality. We can find evidence of this biological antenna in indigenous cultures that have remained connected to their ecosystems for tens of thousands of years, such as the Ashwar tribe in the sacred headwaters of the Amazon. These communities do not view nature as a resource to be exploited or controlled; they function as a keystone species. A true keystone species is a biological participant: wherever it steps, biodiversity, life force, soil health, and ecological beauty increase. The Path to a Biological Renaissance The chemical-antibiotic era has reached its breaking point. Our current health, agricultural, and financial models are going bankrupt because they are built on the false premise of isolation and extraction. However, this crisis is not a hopeless tragedy. It is a necessary transition point. As Dr. Bush observed during his years working in hospice care, death is not an endpoint; it is a transition. In the same way, humanity is currently on its collective hospice bed, preparing to let go of its abstract, mechanical past. Around ten percent of hospice patients do not die; instead, they undergo a profound physical and psychological transition, recover their health, and are discharged to live a completely transformed life. Humanity is standing at this exact threshold. We are on the cusp of a biological renaissance, a period where we will stop trying to control and sterilize our environment and instead focus on restoring our relationship to it. This transition is already visible in our children. The rapid rise of autistic neurology is not a tragedy to be cured with chemicals; it is a biological response to an artificial, abstract world. Autistic children possess highly sensitive, unfiltered neurological systems that function as wide-open antennas. They cannot tolerate cognitive dissonance or artificial environments because they feel everything. They are forcing us to abandon our sterile, machine-like habits and return to a life of genuine connection. Reconnecting with our biological design requires straightforward, deliberate shifts. Studies have shown that spending just three consecutive nights camping in nature, without entering any modern buildings, completely resets the human immune system. Stem cells activate, T-cells turn back on, and our biological age reverses. When we step back into the soil, our bodies remember how to heal. We do not need to invent new technologies to save ourselves. The information needed to rebuild our soils, restore our health, and live in harmony with the Earth is not lost; it is stored in the 98.5% of our DNA that is waiting to be turned back on. By setting aside our obsession with commercialized comfort, chemical control, and financial abstraction, we can open our biological antennas once again and step back into our roles as co-creators of a thriving, living planet.